The symptoms of histamine intolerance are often similar to common allergies, but more pronounced. Supplement-wise I always prefer the natural approach to deal with health issues, and you’ll find that reflected below.
As always, check with your doctor or medical practitioner before changing supplements or starting a new regime. Everybody is different and the content here is for information purposes only.
Overview of supplements featured here
Toxaprevent
Histamine Digest (formerly Histamine Block)
Liposomal Vitamin C
CBD
DAOfood Plus
Probiota HistaminX
HistaminX
Quercetin
Pycnogenol
Colostrum
Grass Fed Kidney for DAO
Loratadine
Magnesium Breakthrough
Adrenal Support
spermidineLIFE®
These supplements in detail
I’ve found a significant long-term benefit to taking Toxaprevent. The tests they’ve carried out on histamine removal in the stomach are fairly astonishing.
Many of my symptoms start in the gut, and this is well worth a go. I take it on an empty stomach with a flare-up, and half an hour before a high-histamine meal too. It is proven to remove the majority of histamine from the gut, and their test results are incredible. This has been one of my go-to histamine supplements, although I recommend starting slowly, as always under the care of your practitioner.
Ships worldwide. Use the code HISTAMINE5 to get 5% discount on all Toxaprevent products.
I have been using Histamine Digest for a long time now (formerly Histamine Block) and it's really great. The idea is you take it just before a high-histamine meal (or drink). Pop two about 15 minutes before you eat. It really is a great help. I never go out without Histamine Block Plus now (my friends roll their eyes when I take out my pill box at the dinner table, but hey, it works…)
Histamine Block Plus is a comprehensive formula containing the histamine-metabolizing enzyme DAO. It includes additional histamine-processing nutrients to support total body histamine breakdown. Check it out here. Use code TONY10 for 10% off. (It’s not that cheap so I just save for when I need it).
Vitamin C is a natural antihistamine that is easy to find. With histamine intolerance, I believe a good liposomal Vitamin C is a must. I use this every day. The interesting bit about this vitamin is that it is apparently a cofactor for diamine oxidase, and also alcohol dehydrogenase. This is the final enzyme that helps in the breakdown of histamine. Whenever you are going through those exhaustive and potent symptoms, taking 1000-1500mg of vitamin C can go a long way in calming you down.
I use Pure Health Liposomal Vitamin C for the purity and bioavailability. Use the code HISTAMINE10 for 10% off. It’s mixed with Sea Buckthorn too which is a bit of a miracle ingredient, and I can pop the sachets in my backpack when I’m out and about too.
I also like Seeking Health (you’ll notice them popping up a lot) Liposomal Vitamin C. Use code TONY10 for 10% off all their products.
Several studies have shown the importance of this vitamin in degrading alcohol by itself. However, you should be careful about the type of vitamin C supplements you buy. Some are laced with heavy metals, which might be toxic to your body (so go to Pure Health or another reputable brand). Always make sure that you only get your supplements from credible sources. Here are the benefits of Vitamin C:
· Helps to relieve a stuffy nose.
· Prevents symptoms of allergies and histamine.
· Helps in the digestion process, among many other metabolic processes.
· Reduces oxidative stress and can act as an effective antihistamine
Pure Health Liposomal Vitamin C will be a good part of your histamine supplement cabinet. Remember to use the code HISTAMINE10
I find CBD helps massively with sleep and relaxation (a huge factor with histamine intolerance).
I only use very pure, organic brands. It is derived from a specific strain of the hemp plant. It is one of many cannabinoids in hemp that has a variety of effects on our body. It really chills me out and I now use CBD often in the evening.
ProBiota HistaminX (use code TONY10 for 10% off) is an excellent supplement from one of my favourite practitioners Dr. Ben Lynch. Incidentally he has some great online resources based on the relationship with histamine and genetics.
His company Seeking Health created this supplement aims at supporting the body’s healthy digestion and microbiome. They created it because many probiotics can cause more harm than good for histamine. This one though contains entirely histamine-friendly strains of bacteria.
It may also aid in boosting the metabolism of histamine taken into the body. ProBiota HistaminX contains probiotics that are safe for the gut and reduce histamine rather can causing a flare up. It helps to reduce the histamine-producing bacteria, and is best to take after your dinner. We like taking it last thing at night. Also, it needs to be kept away from harmful microbials. Some bacterial species produce histamine, while others are essential in breaking it down.
Here are some of the benefits of this supplement:
Helps to tune the gut’s response to the ingested histamine.
Boosts immunity
Helps to enhance the gut microbiome.
Has histamine-friendly probiotics that won’t cause a flare up in your gut.
HistaminX (use code TONY10 for 10% off) is another supplement from Dr. Ben Lynch’s company. It has both herbal and plant-derived compounds that work together to ease inflammation and histamine effects. It is often argued that changes in diets and environment spike different allergies in the body. This supplement helps to prevent these changes from increasing your histamine bucket.
HistaminX is a supplement that also helps to tone down those seasonal allergies that keep on reoccurring. In addition, it prevents the blunt histamine symptoms from draining you.
If you are not having histamine symptoms, you might want to avoid taking the supplement totally, or otherwise take it once in a day. It is a great reliever of running nose, congestion and many other allergies. You should use it alongside medical advice.
Here are some of the potential benefits:
Can alleviate the symptoms of histamine intolerance
Supports the body’s healthy and healing process.
Boosts immune health and well-being.
Can help with seasonal allergies
Supports healthy mucoid membranes. This may be of great help in terms of sinuses and congestion.
This is one of our very favourites. I like BioCare’s Quercetin Plus for the purity and, well, it just seems to work well.
Aside from being a supplement, Quercetin is a compound found in several plants. It is an antioxidant that exists naturally in apples and onions, among many other foods. But you’d have to eat a lot of onions to get the amount found in a supplement. Research-based findings have led to the release of supplements like BioCare containing this compound, due to its antihistamine effects. Depending on your choices or preferences, you can either buy quercetin-rich food (onion-breath alert) or head for the supplements.
As one of the most trusted mast cell stabilizers, quercetin is a potent antioxidant. This supplement controls the mast cells from releasing histamine. As it takes time to be absorbed in the body, many brands recommend it is taken at least 15-30 minutes before your meal.
Here are some of its benefits:
· Reduces allergic symptoms.
· Helps support the body’s ability to quench free radicals
· Reduces inflammatory response that may lead to allergic reactions.
· Reduces respiratory side effects.
· Can help with the side effects of dust, pollen, hay fever and sun.
· Helps with prostate symptoms.
· Is thought to help prevent cancer cell growth in breast, colon, prostate, endometrial and lung.
Tree bark. Amazing innit. This is an extract of the bark of the Pinus Pinaster, otherwise known as French Maritime Tree Bark. Pycnogenol has a potency to fight free radicals in the body. These are by-products of metabolism that are normal in the body, but harmful when in large portions.
Pycnogenol inhibits the release of histamine from the mast cells in the body, and it’s often overlooked in the fight against an allergic response.
· Reduces allergy symptoms and inflammation.
· Wards off free radicals in the body.
· Prevents the release of histamine from mast cells.
· Helps to relieve circulation problems.
It’s not a must have for me, but I take it occasionally and may be worth trying.
This is a type of milk produced by cows (oh and humans), a few days after giving birth. We recommend the Surthrival brand and have had great success using it. Just to be clear – this is cow colostrum not human colostrum, and you always want to use a brand where the newborn have their share of the milk before the supplement is made.
Why is it so good? Colostrum is rich in antibodies. These antibodies help to boost an individual’s immune system. Aside from histamine intolerance, it is popularly used to correct several other complications in the body. Here are some of its known benefits:
· Helps to prevent allergic reactions.
· Ideal for fat burning.
· Helps to ease gastrointestinal challenges.
· Eases diarrhea caused by infections and allergies.
· Suppresses histamine dominance.
Grass-fed kidney is an excellent source of DAO, but let’s face it, who has the time to cook up a load of kidney every day, and then eat it fresh so it doesn’t accumulate histamine in the fridge? DAO, as you now know, is a vital enzyme in the body. DAO regulates the presence of histamine so it’s important. And before a histamine-heavy meal, it’s thought taking a supplement that boosts your DAO level can help.
A good one is the Ancestral Health Grass Fed Kidney – and their customer service is very helpful. You could carry it everywhere and take before meals to boost your DAO levels before a histamine-heavy meal. Sadly this brand is not available in the UK, however there are one or two suppliers to be found in the EU.
Some of the notable benefits of this supplement include the following:
· Is a great source of DAO enzyme.
· Reduces bloating.
· Enhances digestion and other metabolic processes in the body.
· Reduces the severity of eczema.
· Reduces the reaction a person has when ingesting high histamine foods.
As already outlined, I prefer to try natural supplements to over the counter meds. But OTC medicines like Loratadine can provide effective and instant relief and I know if you are reading this, that’s maybe what you need.
Loratadine commonly goes by the name Claritin. It is a remedy for allergies and many people who have used it appreciate its help in terms of reducing itchiness and congestion, among many other symptoms.
Some histamine intolerant people have reported short-term improvements in using Loratadine and other OTCs, but some long-term have found this approach to be less helpful.
Loratadine:
· Helps to contain allergic symptoms such as congestion, sneezing and watery eyes, among many others.
· It helps control the level of histamine in the body.
This might be especially useful in a flare-up or on a seasonal basis.
Magnesium is vital for the human cells, due to several processes. For cells to use energy obtained from food, magnesium must play a role. It is also important for the build-up of muscles and the maintenance of vibrant cell walls. As if this is not enough, the mineral also helps in the maintenance of the DNA structure.
Because of all this, it is thought that histamine intolerance occurs partly due to its deficiency. Apparently magnesium is needed in the production of DAO – an enzyme important for histamine control, as we’ve already discussed.
Therefore if you don’t have sufficient DAO in the body, histamine levels might increase in the body. Most of the symptoms you will go through when intolerant to histamine emanate from the release of histamine from immune cells. This is what, in turn, leads to the allergic reactions.
When you lower the blood histamine levels, you reduce these symptoms and effects. One sure way to achieve this is through the use of magnesium.
My current favourite is Magnesium Breakthrough, containing the seven important forms of magnesium, all in one pill. I use it every day. Do your research on Magnesium Breakthrough, and if you decide to go for it, use code ZESTOLOGY10 anywhere in the world for 10% off. Let me know how you get on. Epsom salts also work well. The only thing you should note when using the bathing salts is that heat accelerates histamine levels (little known fact!) You could consider using lukewarm water instead of hot water, or just having an Epsom salts footbath.
Look at adrenal support and the link between that and histamine. We know we’ve mentioned him already but we really like Dr. Ben Lynch’s Seeking Health supplements for adrenal support. (use code TONY10 for 10% off)
If you think your adrenals might be taxed by all this stress around the histamine, then check out his supplements, in particular Optimal Adrenal and Adrenal Cortex.
Studies have shown spermidine may transform your cellular health, cardiovascular function, and improve memory, immune function and sleep by enhancing autophagy.
spermidineLIFE® is the only clinically tested spermidine supplement worldwide that promotes cellular health and longevity, allowing you to live young for as long as possible. I’m recommending it because of its powerful sleep and cell renewal benefits. That has to be good for histamine intolerance. (That said, I would love to find specific research on spermidine and histamine). Visit here and use code TONY20 at checkout to get 20% off.
I know this is an area that people love talking to me about so I’ve focused on it in my online program. There’s lots more on supplements and my new personal favourites for methylation in my masterclass. It’s really worth digging into the supplements section, particularly on methylation - here’s a link to my masterclass - From Histamine Intolerance To Healed.
There is a big section on supplements and I really dig in on my current favourites.
After you’ve taken the program, feel free to reach out with any questions.